Follistatin 315 Myostatin Blockers

Follistatin 315 Myostatin Blockers

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details


Follistatin 315

Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


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Follistatin 315 Description

  • Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.

  • The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA.

  • Follistatin is a secreted glycoprotein that was first identified as a folliclestimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGF like and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.

Follistatin 315 Applications

  • Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.

  • Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it.

  • Follistatin 315 primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.

  • Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.


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