Hexarelin Peptides 2mg CAS 140703-51-1

Hexarelin Peptides 2mg

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Hexarelin

Sequence: His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
Molecular formula: C47H58N12O6
Molar Mass: 887.04022
CAS number: 140703-51-1
PubChem: CID 5464109
Synonyms: HNAcetate, HEX, Examorelin


Application

Ghrelin is an appetite-regulating factor secreted from peripheral organs that is involved in regulation of energy homoeostasis via binding to the receptor resulting in the secretion of by the pituitary gland. The pathway activated by binding of ghrelin to the secretagogue receptor, GHSR1a, regulates the activation of the downstream mitogen-activated protein kinase, Akt, nitric oxide synthase, and AMPK cascades in different cellular systems.

One of the important features of GHSR1a displays constitutive activity possessing basal activity in the absence of an agonist, resulting in a high degree of receptor internalization as well as of signaling activity.Inverse agonists for the ghrelin receptor could be particularly interesting for the treatment of obesity.This activity seems to provide a tonic signal required for the development of normal height, probably through an effect on the GH axis.

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  1.Our company is a professional raw powder factory in China for over 10  years, all powders are factory directly supplying.

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