Melanotan II Mt-2 Melanotan MT2 Tans

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details


Melanotan-II (MT-II)


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


Product Name:Melanotan II melanotan 2(MT-2)


Storage :Lyophilized Melanotan II is stable at room temperature for 90 days,however it should be stored in a freezer below -8C for any extended period of time. After reconstituting Melanotan II should be refrigerated at temperatures not to exceed 36 F.

Melanotan-II Specification:

ITEM

SPECIFICATION

Appearance

White Crystalline Powder

Assay

≥99%

Heavy Metals

≤10ppm

Arsenic

≤1ppm

Lead

≤3ppm

Mercury

≤0.1ppm

Cadmium

≤1ppm

Total Plate Count

≤1000cfu/g

Yeast & Mold

≤100cfu/g

E.Coli

Negative

Salmonella

Negative

Conclusion

The product conforms to the standard.


Melanotan-II Mechanism of action:
Melanotan II acts as a non-selective agonist of the melanocortin receptors, MC1, MC3, MC4, MC5. Like other melanocortinergic peptides, such as the melanocyte-stimulating hormones (MSHs) and afamelanotide, but unlike adrenocorticotropic hormone (ACTH), melanotan II lacks affinity for the MC2 receptor. Reported activity of the drug is as follows:

MC1 (Ki = 0.686 nM)
MC2 (Ki > 1000 nM)
MC3 (Ki = 34.1 nM)
MC4 (Ki = 6.60 nM
MC5 (Ki = 46.1 nM)

The melanogenesis produced by melanotan II is caused by activation of the MC1 receptor, whereas its sexual effects are thought to be related to its ability to activate the MC4 receptor (though the MC3 is thought to possibly also be involved). Other effects of melanotan II, mostly regarded as adverse effects, include flushing, nausea, vomiting, stretching, yawning, and loss of appetite (the last via activation of MC4).

Melanotan II produces bremelanotide, which, comparatively, is reported to be approximately 50-fold more potent as an inducer of sexual arousal in rats, as an active metabolite.


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