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Product Name: Serrac (10mg)
Appearance: white solid
Category: Pharmaceutical Raw Materials
Deferred products: Injection
Use: Increased: seen in stress states, primary adrenal insufficiency, Cushing syndrome, Nelson syndrome, congenital adrenal hyperplasia, and pituitary adrenocorticocytoma. Decrease: seen in hypopituitarism, adrenal cortical tumors, pituitary tumors, and anterior pituitary lesions.
Usage and dosage: After oral administration, CTH is destroyed by pepsin in the stomach and can only be injected. Plasma t1/2 is 15 minutes. It is at normal plasma concentrations of 22 pg/ml at 8 am and 9.6 pg/ml at 10 pm. Its main role is to promote the secretion of glucocorticoids, but only when the cortical function is intact can play a therapeutic role. Typically, the cortex begins to secrete hydrocortisone 2 hours after administration.
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