Terlipressin Acetate Peptides 14636-12-5
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Cas No.: 14636-12-5
Molecular Formula: C52H74N16O15S2
Molecular Weight: 1227.37
Purity (HPLC): 98.0%min.
Appearance: White powder
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): >=80.0%
Water Content(Karl Fischer):>=10.0%
Specific Rotation (20/D): -95.0~-105.0°(c=1 1%HAc)
Acetate Content (HPIC): <=15.0%
Mass Balance: 95.0~105.0%
Storage: Closed, below 2 ~ 8ºC preservation
Delivery time : within 24 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage : Norepinephrine-resistant septic shock, bleeding esophageal varices, and for the complications of cirrhosis of the liver (esophageal and gastric variceal bleeding, ascites, liver and kidney syndrome) has important significance for the treatment of patients
Terlipressin is a novel long-acting synthetic vasopressin reagent; it is a prodrug, itself has no activity ,in vivo, it removes three glycyl residues in its N-terminus by aminopeptidase, and slowly "releases" the active lysine vasopressin. It is this "slow release" mechanism that makes it maintain the smooth muscle contraction up to 10 hours after a single administration, whereas the same dose of vasopressin, it can maintain its activity for 20-40 minutes. On the other hand,because of the slow digestion, lysine vasopressin in the circulation cannot reach toxic levels, and usage of terlipressin is safer.
This product is pressurized prodrug hormone, vasopressin glycyl in injection into the blood after enzymatic hydrolysis in the molecule is produced a continuous low level. The portal venous pressure it generates the desired effect, but the changes of arterial blood pressure than the use of vasopressin after much smaller, and the blood of a few do not increase the fibrinolytic. Push once its role can be maintained for about 4 ~ 6h.
Intravenous injection, 2mg, every 4 ~ 6h again, until the control, use at most 24h. It is not for children.
Products list of Peptide:
|Products Name||Products CAS|
|Thymosin α1 Acetate||62304-98-7|
|Thymosin β4 Acetate||77591-33-4|
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