Triptorelin 2mg

Triptorelin 2mg

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details

Triptorelin Acetate
 

Contact : Mr.Thyen   

Email us at zhangyinglong@ycphar.com   

Whatsapp : +86 180 3817 6818

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Triptorelin Acetate CAS No.: 57773-63-4 
Triptorelin Acetate Sequence:GLP-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-PRO-Gly-NH2
Triptorelin Acetate Purity (HPLC): 98.0% min.
Triptorelin Acetate Appearance: White powder
Molecular Formula: C64H82N18O13
Molecular Weight: 1311.46
Single Impurity (HPLC): 1.0%max
Amino Acid Composition: ±10% of theoretical
Peptide Content (N%): ≥80.0% 
Water Content(Karl Fischer): ≤6.0%
Triptorelin Acetate Acetate Content (HPIC): ≤15.0%
Triptorelin Acetate MS(ESI): Consistent
Triptorelin Acetate Mass Balance: 95.0~105.0%
Triptorelin Acetate Specific Rotation (20/D): -65.0~-75.0°(c=0.5 1%HAc)


Triptorelin (GnRH)
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. Triptorelin raises testosterone levels by causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. Triptorelin is marketed under the brand names Decapeptyl (Ipsen) and Diphereline and Gonapeptyl (Ferring Pharmaceuticals). In the United States, it is sold by Watson as Trelstar.In Iran Triptorelin is marketed under the brand name Variopeptyl (Varian Darou Pajooh). In India, Dr. Reddy's Laboratories has launched recently Triptorelin under the brand name "Pamorelin LA". During the treatment of prostate cancer it does cause a surge of testosterone (an initial uplevel of testosterone levels), known as a flare effect. In men a reduction of serum testosterone levels into the range normally seen after surgical castration occurs approximately two to four weeks after initiation of therapy. 


 

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