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Lidocaine, also known as xylocaine and lignocaine is a medication used to numb tissue in a specific area and to treat ventricular tachycardia. It can also be used for nerve blocks. Lidocaine mixed with a small amount of adrenaline (epinephrine) is available to allow larger doses for numbing, to decrease bleeding, and to make it last longer. When used as an injectable, it typically begins working within four minutes and lasts for half an hour to three hours. Lidocaine may also be applied directly to the skin for numbing.
Lidocaine Quick Detail:
Product Name: Lidocaine
Synonyms: Lidocaine; Lidocaine hcl; Lidocaine Hydrochloride; Lidocaine base
Molecular Formula: C14H23N2O
Molecular Weight: 235.3447
Usage :pharmaceutical raw materials, the hormone
Packaging Details: Foil bag or as requirement
Payment Terms: T/T, Western Union, MoneyGram
Shipping way: EMS, HKEMS, DHL, TNT, Fedex, UPS… (you can choose the fastest and your favourite)
Lidocaine (INN, BAN) , xylocaine, or lignocaine (AAN, former BAN) is a common local anesthetic and class-1b antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning, and pain from skin inflammations, injected as a dental anesthetic, or used as a local anesthetic for minor surgery.
Lidocaine crosses the blood-brain and placental barriers, presumable by passive diffusion.
Lidocaine is metabolized rapidly by the liver, and metabolites and unchanged drug are excreted by the kidneys. Biotransformation includes oxidative N-dealkylation, ring hydroxylation, cleavage of the amide linkage, and conjugation. N-dealkylation, a major pathway of biotransformation yields the metabolites monoethylglycinexylidide and glycinexylidide. The pharmacological/toxicological actions of these metabolites are similar to, but less potent than, those of Lidocaine. Approximately 90% of Lidocaine administered is excreted in the form of various metabolites, and less than 10% is excreted unchanged. The primary metabolite in urine is a conjugate of 4-chydroxy-2, 6-dimethylaniline.
It is the most important medications needed in a basic healthcare system.
White crystalline powder
Appearance of solution
Clear and colourless
Meet the requirement
The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy.
Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action. Epinephrine (adrenaline) vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful.
Lidocaine drops can be used on the eyes for short ophthalmic procedures.
Lidocaine, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.
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