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Product name: Mepivacaine HCL
Other name: Mepivacaine hydrochloride
Appearance: white crystals powder
Grade: Pharmaceutical grade
Package: Disguised package ; Foil bag
Delivery date: 3-5 work days
Certificate: ISO 9001, USP,GMP
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White crystalline powder
Mepivacaine HCL is a local anesthetic for amides. The incidence of mepivacaine is relatively fast (much faster than procaine) and medium-term effects (shorter than probucol) and are sold under a variety of trade names, including caracaine and pucaine The
Mepivacaine HCL is used in any infiltration and local anesthesia, provided in the form of a racemate hydrochloride.
Functional food and food additives
Mupivacaine hydrochloride to stabilize the neuronal membrane, to prevent the occurrence and spread of nerve impulses, and thus local anesthesia.
The rapid metabolism of mepivacaine hydrochloride, only a small part of the anesthetic (5% to 10%) excretion in the urine unchanged. Methapine is not detoxified by circulating plasma esterase because of its amide structure. The liver is the main site of metabolism, more than 50% of the dose as a metabolite is excreted into the bile. Most metabolized mepivacaine may be absorbed in the intestine and then excreted into the urine because only a small fraction is found in the feces.
The main way to excrete is through the kidneys. Most anesthetics and their metabolites are eliminated within 30 hours. It has been shown that hydroxylation and N-demethylation as detoxification play an important role in the metabolism of anesthetics. Three metabolites of mepivacaine have been identified from adults: two phenols are almost completely excreted as glucuronide conjugates, and N-demethylated compounds (2 & apos;, 6 & apos; Oxygen).
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The onset of the action is fast (maxillary 30 to 120 seconds, jaw 1 to 4 minutes), 3% injection of mepivacaine hydrochloride hydrochloride No vasoconstrictor usually provides 20 minutes of surgery in the upper jaw anesthesia, mandibular.
Mabepacaine hydrochloride usually does not produce irritation or tissue damage.
Dose and management
As with all local anesthetics, the dose varies and depends on the area to be anesthetized, the vascular distribution of the tissue, individual tolerance and anesthesia. The minimum dose required for effective anesthesia should be given. Specific technical and procedural references Standard dental manuals and textbooks. For osmotic and obstructive injections in the upper and lower jaws,
the average dose of a cartridge is usually sufficient. Each cartridge contained 1.8 mL (54 mg 3% solution). Five cartridges (270 mg of 3% solution) are usually sufficient to affect the entire oral anesthesia. Whenever a wider dose seems to be necessary, the maximum dose should be calculated based on the patient's weight. A dose of up to 3 mg per pound of body weight may be administered. At any dental clinic, the total dose for all injections should not exceed 400 mg in adults.
The maximum pediatric dose should be calculated carefully.
Systemic adverse reactions involving the central nervous system and the cardiovascular system are usually caused by high levels of plasma due to excessive doses, rapid absorption or unintentional intravascular injection.
A small part of the reaction may be caused by a patient's hypersensitivity, specificity, or reduced tolerance to a normal dose.
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