Prilocaine Base

Prilocaine

CAS:721-50-6

MF:C13H20N2O

MW:220.31

EINECS:211-957-0

Synonyms:astra1512 ;astra1515 ;Citanest;L 67;l67 ;n-(2-methylphenyl)-2-(propylamino)-propanamid ;o-Methyl-2-propylaminopropionanilide;o-Methyl-alpha-propylaminopropionanilide

Usage

Prilocaine topical may also be used for other purposes not listed in this medication guide.
For a variety of surgical epidural block and infiltration anesthesia Prilocaine topical is a local anesthetic (numbing medication).It works by blocking nerve signals in your body.Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.

Description

Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren.In its injectable form (trade name Citanest), it is often used in dentistry.It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

Applications

Prilocaine topical is a local anesthetic (numbing medication).It works by blocking nerve signals in your body. Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.

Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of
intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade
name Novocain, in some regions procaine is referred to generically It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine was first synthesized in 1905,shortly after amylocaine.It was created by the German chemist Alfred Einhorn who gave the chemical the trade name , from the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics.It was introduced into medical use by surgeon Heinrich Braun. Prior to the discovery of amylocaine and procaine, was the most commonly used local anesthetic. Einhorn wished his new discovery to be used for amputations, but surgeons preferred general anesthetic. Dentists, however, found it very useful. Einhorn was displeased by this and spent many years touring dental schools to advise them not to use it.

Specification

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