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CAS No.: 1786-81-8
EINEC No.: 217-244-0
Boiling point: 361.6 ° C at 760 mmHg
Flash point: 134.3 ° C
Steam pressure: 2.05E-05mmHg at 25 ° C
Appearance: White crystalline powder
Propitocaine hydrochloride is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form, it is often used in dentistry. It is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia.
As it has low cardiac toxicity, it is commonly used forintravenous regional anaesthesia.Local anesthetics, long duration, lower toxicity, chemicals that are also small Suitable for epidural anesthesia, block anesthesia and infiltration anesthesia, etc.
A local anesthetic of the amino ester group that is primarily used as a topical anesthetic.Also used to control the pain of intramuscular injection of penicillin as well as in dentistry.Non Caine local anesthetic.
Prilocaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.
Propitocaine HCl Application :
Prilocaine is a local anesthetic of the amino amide type. Prilocaine is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/pril ocaine or EMLA), for treatment of conditions like paresthesia.
Local anesthetic is a substance that causes loss of sensation only to the area to which it is applied without affecting consciousness. Most local anesthetics structures have amino-ester or an amino-amide group which are linked to hydrophilic (secondary or tertiary amine).
The ester can be hydrolysed in plasma by the enzyme pseudocholinesterase into PARA-aminobenzoic acid. Amide is stable for longer acting and more systemic distribution. Ester types include Procaine (Novocain), Chloroprocaine (Nesacaine), Tetracaine (Pontocaine), Benzocaine, Tetracaine. Amide types include Lidocaine (Xylocaine), Mepivacaine(Carbocaine), Prilocaine (Citanest), Bupivacaine (Marcaine), Etidocaine (Duranest).
134.3 ° C
168-170 ° C
2.05E-05mmHg at 25 ° C
361.6 ° C at 760 mmHg
Loss on drying
66-69 ° C
Pharmaceutical raw materials
White crystalline powder, odorless, a little bitter
Store in sealed containers at cool & dry place. Keep away from light, moisture
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