Azathioprine Powder CAS 446-86-6

Azathioprine Powder CAS 446-86-6

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details

Azathioprine Powder CAS 446-86-6

Contacting Information :

Contact person : Thyen

Skype :live:simeiquan-zhang

WhatsApp : +8618038176818

E-mail : zhangyinglong@ycphar.com

Website : www.sellsteroid.com


Product name: Azathioprine
Alias: Imurel; Azathioprin; Azanin; Imuran; azatihoprine;
CAS number: 446-86-6
EINECS Number: 207-175-4
Molecular formula:C9H7N7O2S
Molecular weight: 277.26300
Exact mass: 277.03800
PSA: 143.40000
LogP: 1.66900
Appearance and traits: light yellow crystalline powder
Density: 1.9 g/cm3
Melting point: 243-244°C
Boiling point: 685.7oC at 760 mmHg
Refractive index: 1.923
Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
Storage conditions: ventilation and low temperature drying
Steam pressure: 7.98E-12mmHg at 25°C
Symbols:
GHS07
GHS08
Signal Word: Danger
Hazard statement: H302; H315; H319; H335; H350
Cautionary statements: P201; P261; P305 + P351 + P338; P308 + P313
Customs Code: 2933990090
Hazard Category Code: R45
Safety instructions: S53-S22-S26-S36/37-S45
RTECS number: UO8925000
Dangerous goods signs: Xi; T; Xn

Azathioprine is an imidazole derivative of purine that functions to decompose to purine in the body. The mechanism of its immune action is the same as that of purines, that is, it has purine antagonism. Since purine substances are required for the proliferation of immunocompetent cells after antigen stimulation, purine antagonism at this time can inhibit the synthesis of DNA, RNA, and protein, thereby inhibiting Proliferation of lymphocytes, ie, the prevention of transformation of antigen-sensitive lymphocytes into immune mother cells, produces an immune effect.

 

Azathioprine COA:
 


Product name
Azathioprine

CAS No.

446-86-6

Outer Packing
5kg/bag

Production date

2017.09.24

Shelf life

2020.09.23

Standard adopted

USP35

Items of analysis

Specification

Results

Appearance

Pale yellow powder

Conforms

Identification

A: IR B: TLC

Conforms


Acidity or Alkalinity

NMT 0.1ml of HCL 0.020N or NMT 0.1 ml of NaOH 0.020N


Conforms

Loss on Drying

1.0 %Max

0.35%

Residue On Ignition

0.1 %Max

0.06 %

Mercaptopurine (TLC)

1.0 %Max

Conforms

Assay(dry basis)

98.0-101.5%

99.8%

Conclusion

Qualified


application

It is mainly used for anti-rejection during organ transplantation. It is mostly used together with corticosteroids or anti-lymphocyte globulin (ALG), which has good curative effect. It is also widely used in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, active chronic hepatitis, ulcerative colitis, myasthenia gravis, and scleroderma. For chronic nephritic and nephrotic syndrome, the efficacy seems to be inferior to cyclophosphamide. Because of its serious and serious adverse reactions, the treatment of these diseases is not the preferred drug, and it is usually used when corticosteroids alone cannot be controlled.

Precautions

This product can cause bone marrow suppression, liver damage, teratogenic and so on. This product must not be opened or crushed. The outer packaging must not be accepted after it has been ruptured. It is harmless to carry the complete film product and it is not necessary to take other protective measures. Or follow the doctor's advice.
Patients with renal insufficiency should be appropriately reduced. Symptomatic treatment is generally used for overdose, and severe cases may be considered for dialysis.
Medication taboo editing
People with impaired liver function are disabled. Pregnant women use it with caution.


Payments


As far as payment methods are considered, we accept a number of secure payment methods, customers can pay to us through any of the payment methods mentioned below:-


Western Union: Western Union Money Transfer, a very famous and secure money transfer method is accepted by us. Our customer who desire to pay us through this method can transfer payment to us by using WU. To pay us through WU, after placing your order, go to your nearest WU franchise, make the payment there and confirm us the MTCN. After receiving the payment we will process your order.


Money Gram: We also accept Money Gram, to pay us through Money Gram, after placing your order please contact us to get the payment sending details. After that, go to your nearest Money Gram franchise, make your payment and confirm us the Reference  Number provided by the money gram at the above email address.



We accept payments via Western Union or Money Gram only. We don’t accept PayPal anymore, that we were doing in past but now we are not able to use PayPal anymore.(Some of the products we deals in are highly banned, so credit card and bank wire will not be the safe & secure for both of buyer and seller. For these type of orders, Western Union and Money Gram are most safe and secure payment methods).



Bit Coins: Bit Coins are also accepted by us, if you want to pay us through Bit Coins, please contact us, we will send you our Bit Coin address, you will send us payment at that address and we will ship your order.

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