Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818

What is Cetilistat?

Cetilistat is a drug designed to treat obesity. It acts in the same way as the older drug orlistat by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine. Without this enzyme, triglycerides from the diet are prevented from being hydrolyzed into absorbable free fatty acids and are excreted undigested.It results in weight loss and absorbs fat from diet. The drug acts peripherally to reduce the appetite, without affecting the brain.



Product Name


CAS: 282526-98-1

Items Tested







White to off white powder

White to off white powder




Melting point

72 °C ~ 75 °C

72 °C ~ 73 °C

Loss on drying

≤1.0 %


Residue on Ignition



Sulphate ash



Related substance

≤1.0 %

0.1 %

Heavy metals

≤ 20 ppm



Enterprise Standard

How Cetilistat works?

Cetilistat is a drug designed to treat obesity. when this medicine is administered alongside a meal, it binds to the lipases, thereby inhibiting them from breaking down the fat. Fats which are not hydrolyzed are instead excreted in the feces, resulting in increased fecal fat excretion and reduced fat absorption. When used together with a reduced calorie diet, it can help improve weight loss and make it easier for overweight patients to get back in shape, thereby boosting the chances of successful weight loss.


How to use Cetilistat

Cetilistat is usually taken orally as directed by a doctor. The medication can be taken with, during or even up to 1 hour after each main meal. If you skip a meal, do not take the medication. Swallow the capsules whole with a glass of water. Contact a doctor for the correct dosage and length of treatment as it will depend on the patients condition and their response to the therapy.


Therapeutic Approaches to Treatment of Obesity

The growing prevalence of obesity has stimulated the search for drugs to treat this condition. Various therapeutic strategies have been explored, including:

Serotonin and noradrenaline reuptake inhibitors (anorectic agents)
Lipase inhibitors
b 3-adrenoreceptor agonists
Leptin agonists
Melanocortin-3 agonists
Endocannabinoid receptor antagonists

Cetilistat is a lipase inhibitor, with a similar mode of action to Roche's anti-obesity medication orlistat (Xenical®) which received regulatory approval in 1997. These drugs act in the gastrointestinal tract to inhibit lipases, enzymes involved in the breakdown of dietary fats. By inhibiting the breakdown and subsequent absorption of fats from the gut, lipase inhibitors reduce fat intake and calories, thus aiding weight loss.


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