Eplerenone CAS 107724-20-9
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|Certification||ISO 9001, USP, BP|
|Description||White or Almost White Crystalline Powder||white powder|
|Loss On Drying||1.0%max||0.27%|
|Organic Volatile Impurities||meets the requirement.||Conforms|
|Related Substances||meets the requirement.||Conforms|
|Residual Solvents||meets the requirement.||Conforms|
|Particle Size||100% ≤ 20 microns||Conforms|
|Conclusion||The specification conform with USP30 standard|
Eplerenone is an aldosterone antagonist used as an adjunct in the management of chronic heart failure.
Eplerenone is similar to the diuretic spironolactone, though it is much more selective for the mineralocorticoid receptor in comparison and is specifically marketed for reducing cardiovascular risk in patients following myocardial infarction.
Eplerenone is marketed by under the trade name Inspra. Eplerenone is a potassium-sparing diuretic, meaning that it helps the body get rid of water but still keep potassium.
Eplerenone is used alone or in combination with other medications to treat high blood pressure.
Eplerenone is in a class of medications called mineralocorticoid receptor antagonists.
Eplerenone works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure