Megestrol acetate
Megestrol acetate Product Name:Megestrol acetate
Megestrol acetate CAS:595-33-5
Megestrol acetate MF:C24H32O4
MW:384.51
EINECS:209-864-5
mp：214°C
Megestrol acetate refractive index：11°(C=2, CHCl3)
Megestrol acetate Chemical Properties：Crystalline Solid
Megestrol acetate Usage：Progestogen;Progesterone receptor agonist,Orally active progestogen; formerly used in combinations as oral contraceptive,treatment of endometrial hyperplasia
Megestrol acetate COA
Test Items Specification Test Results
AppearanceWhite to creamy white crystalline powderWhite crystalline powder
IdentificationIRComplies
Completeness of solutionMeets the requirements.500mg being Complies
dissolved in 10ml of acetone
SolubilityInsoluble in water, sparingly soluble in Complies
alcohol. Slightly soluble in ether and in
fixed oils, soluble in acetone; very soluble
in chloroform.
Melting range213℃~220℃ 217℃
Specific optical rotation+8.8°~ +12.0°+11.6°
Water≤0.5%0.1%
Residue roration≤0.2%0.06
Heavy metals≤0.002%Complies
Assay97.0%~103.0%99.6%
Residual solventsMethanol≤1000ppm74ppm
Ethanol≤1000ppm39ppm
Methylene chloride≤500ppm28ppm
Tetrahydrofuran≤300ppmND
Benzene≤2ppmND
Megestrol acetate Product Tags：Megestrol acetate、595-33-5
