Melatonine/ CAS:73-31-4
Product Name:Melatonine
Synonyms:Acetamide
CAS:73-31-4
MF:C13H16N2O2
MW:232.28
EINECS:200-797-7
mp:116.5-118 °C(lit.)
Chemical Properties:Off-White Powder
Mechanism: melatonin, also known as melatonin, a hormone secreted by the pineal gland cells, the chemical structure is 5-methoxy -N- acetyl serotonin, its physiological role for the inhibition of the gonads, thyroid, adrenal, parathyroid and pituitary function, inhibition of precocious puberty, reduce the secretion of pituitary melanocyte; and having a central nervous system, it can increase seizure threshold, causing drowsiness.
Uses: Melatonin for medicine and health products, can enhance the body's immune function, prevent aging rejuvenate, and is a natural "sleeping pills."Immunostimulant;Melatonin receptor ligand,sleep induction, modifies circadian rhythm, antioxidant, free radical scavenger
Cosmetics: Melatonin is mainly used for cosmetic whitening moisturizer.
Anti-aging effects: may generate free radicals in the body and non-enzymatic reaction of enzymatic reactions, free radicals and aging are closely linked. Produce normal body and eliminate free radicals in a dynamic equilibrium, once this balance is broken, it will cause a radical biological macromolecules such as lipids, proteins, nucleic acids damage, leading to the destruction of cell structure and aging of the body. Melatonin by scavenging free radicals, anti-oxidation and inhibition of lipid peroxidation protection cell structure to prevent DNA damage, reduce the content of peroxides in vivo
Application of melatonin in breast cancer
Breast cancer is the second most common cancer in the world of women, after lung cancer mortality is following in second place of the tumor, its incidence in recent years in the world increased year by year. Melatonin secretion of the pineal gland in the human body as a hormone, past a large number of studies have confirmed the physiological concentrations of melatonin on estrogen receptor (ER) positive breast cancer cells was inhibited by exogenous melatonin can significantly mitigate anthracycline-induced cardiotoxicity.
Melatonine COA:
Product nameMelatonin
ItemSpecifications
CharacteristicsWhite or pale-white crystalline powder
Identificationpositive reaction
Particle size80-120 mesh
Loss on drying0.5% MAX
Melting point117~120C
Heavy metal10ppm MAX
Residue on ignition0.1% MAX
Assay(HPLC)99.0%MIN
