Miconazole Nitrate
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Miconazole nitrate Product Name: Miconazole nitrate
Miconazole nitrate CAS: 22832-87-7
Miconazole nitrate MF: C18H15Cl4N3O4
Miconazole nitrate MW: 479.14
Miconazole nitrate EINECS: 245-256-6
Miconazole nitrate Melting point : 170-185 C
Miconazole nitrate Storage temp. : Store at RT
Miconazole nitrate Chemical Properties White Solid
Miconazole nitrate Usage An antifungal agent that inhibits platelet cyclooxygenase
Miconazole nitrate Usage Antifungal (topical).
Miconazole nitrate Product Categories: Active Pharmaceutical Ingredients;Organics;Antifungals for Research and Experimental Use;Biochemistry;API's;Antifungal;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;MONISTAT;API
Miconazole nitrate Description
Miconazole nitrate is a kind of antifungal agent which is the drug ”Dakelin” which we are familiar with as commonly used drugs for treating skin ringworm. It has various kinds of effects. It inhibit the biosynthesis of ergosterol which is the fungal cell membrane component, causing damage to the cell membrane structure, increasing the membrane permeability, resulting in the leakage of the intracellular components and inhibiting the glucose utilization, preventing the nutrient uptake, and finally leading to fungal cell death.
Miconazole nitrate is therefore suitable for the treatment of tinea, jock itch, ringworm, athlete's foot, tinea versicolor and paronychomycosis as well as the vaginal infection and secondary infection caused by the yeast (such as Candida) and Gram-positive bacteria.
Miconazole nitrate is also effective in treating otitis externa and bacterial skin infections.The common adverse reactions and side effects of miconazole nitrate include: occasional allergy, blisters, burning feeling, redness, itching or other skin irritation. Very rare angioedema, urticaria, eczema, contact dermatitis, erythema, pelvic pain (cramps), vaginal irritation, vaginal secretions and discomfort in the administration site.
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