Minoxidil For Hair Loss

Minoxidil For Hair Loss

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Product Details

Minoxidil


Product Name:1,3,5(10)-Estratrien-3-ol-17-one

Synonyms:(8R,13S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one

CAS:53-16-7

MF:C18H22O2

MW:270.37

EINECS:200-164-5

mp 258-260 °C(lit.)

alpha:158 º (c=1, dioxane)

refractive index:165 ° (C=1, Dioxane)

Chemical Properties:Crystalline Solid

Usage:A metabolite of 17β-Estradiol.estrogen,Intermediate of Ethinyl estradiol. 


AppearanceWhite crystalline powder

Package1kg/aluminium foil bag or as required

Usagecan be used as pharmaceutical material

Minimum order quantity10g

passmentProfessional team special for package and shipment and staring

on tracking code 24hours for customs pass guaranteed

ShippingBy express courier

Shipping leading timeWithin 24 hours after receiving the payment

Payment optionsWestern Union, MoneyGram, T/T,Bank transfer

shipping1)Express delivery with DHL,EMS,Fedex,HKEMS,TNT,UPS

(Express delivery within 24 hours after payment)

2)By sea (large quantity ,it will take 30-45days)

PriceNegotiated

Supply ability500kg/Month


Brief introduction:

Minoxidil is an antihypertensive vasodilator medication. It also slows or stops hair loss and promotes hair regrowth in some people. Now off-patent, it is available over-the-counter for the treatment of androgenic alopecia.


Medical uses

Minoxidil, applied topically, is widely used for the treatment of hair loss. It is effective in helping promote hair growth in both males and females with androgenic alopecia.About 40% of men experience hair regrowth after 3-6 months. Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. It is the only topical product that is FDA approved for androgenic hair loss.Treatments usually include a 5% concentration solution that is designed for men, and a 2% concentration solution for women.

The drug is available in the United Kingdom over-the-counter.

Its effect in people with alopecia areata is unclear.


Mechanism of action

The mechanism by which minoxidil promotes hair growth is not fully understood. Minoxidil is a potassium channel opener, causing hyperpolarization of cell membranes. Minoxidil is less effective when there is a large area of hair loss. In addition, its effectiveness has largely been demonstrated in younger men who have experienced hair loss for less than 5 years. Minoxidil use is indicated for central (vertex) hair loss only. Minoxidil is also a vasodilator.Hypothetically, by widening blood vessels and opening potassium channels, it allows more oxygen, blood, and nutrients to the follicle. This may cause follicles in the telogen phase to shed, which are then replaced by thicker hairs in a new anagen phase. Minoxidil is a pro-drug activated by sulfation via the sulfotransferase (SULT1A1). Several studies demonstrated that the activity of sulfotransferase in hair follicles predict minoxidil response in the treatment of hair loss.Two clinical studies are being conducted in the US for a medical device that may allow patients to determine if they are likely to fail minoxidil therapy.


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