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HSE, ISO 9001, USP, BP
antiulcerative;prostaglandin E1 analog that inhibits gastric acid secretion
Discreet packing ways as your requirement, 100% go through.
Store in cool and dry area and keep away from direct sunlight.
Misoprostol is a medication used to start labor, induce abortions, prevent and treat stomach ulcers, and
treat postpartum bleeding due to insufficient contraction of the uterus. For abortions it is used with
mifepristone. It is a synthetic prostaglandin E1 (PGE1).
Common side effects include diarrhea and abdominal pain. It is pregnancy category X meaning that it is
known to result in negative fetal outcomes if taken during pregnancy. Uterine rupture may occur.
Misoprostol acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled
receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP
levels and decreased proton pump activity at the apical surface of the parietal cell. Because other classes
of drugs, especially H2-receptor antagonists and proton pump inhibitors, are more effective for the
treatment of acute peptic ulcers, misoprostol is only indicated for use by people who are both taking
NSAIDs and are at high risk for NSAID-induced ulcers, including the elderly and people with ulcer
Misoprostol is sometimes coprescribed with NSAIDs to prevent their common adverse effect of gastric
ulceration. Misoprostol has other protective actions, but is only clinically effective at doses high enough to
reduce gastric acid secretion. For instance, at lower doses, misoprostol may stimulate increased secretion of the protective mucus that lines the gastrointestinal tract and increase mucosal blood flow, thereby increasing mucosal integrity. However, these effects are not pronounced enough to warrant prescription of misoprostol at doses lower than those needed to achieve gastric acid suppression.