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Product Name: Orlistat
Appearance: White crystalline powder
Use:An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Orlistat is an pancreatic lipase inhibitor. Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin is widely used for the treatment of obesity.
White to kind of white powder
kind of white powder
Soluble in methanol
Residue on ignition
Up to the Standard USP 32.
Orlistat (also known as tetrahydrolipstatin) is a drug designed to treat obesity. In most countries, it is sold under the trade name of Roche as a prescription drug and sold by GlaxoSmithKline in the UK and the United States. Its main function is to prevent the intake of fat in the body's diet as a lipase inhibitor, thereby reducing calorie intake. It applies to low-calorie diets that health care providers supervise.
The effectiveness of orlistat in promoting weight loss is clear, albeit moderately. The pooled data from clinical trials show that people who give olivide have less than 2-3 kilograms (4.4-6.6 pounds) of medication than a year, except for changes in lifestyle such as diet and exercise. Is also a modest reduction in blood pressure, it seems to be able to prevent the onset of type 2 diabetes, whether due to weight loss itself or other effects; in a large randomized controlled trial, orlistat he was found in obese people will reduce the incidence of diabetes by nearly 40% Before Taking This Medicine
You should not take orlistat if you are allergic to it, or if you have:
chronic malabsorption syndrome (an inability to absorb food and nutrients properly); or
if you are pregnant.
To make sure orlistat is safe for you, tell your doctor if you have:
a history of gallstones or kidney stones;
a history of pancreatitis;
type 1 or type 2 diabetes;
an eating disorder (anorexia or bulimia); or
if you take any other weight-loss medications (prescription or over-the-counter).
1) Usual Adult Dose for Obesity:
120 mg orally three times a day with each main meal containing fat. The dose may be taken during the meal or within 1 hour of completing the meal.
Your daily intake of fat, carbohydrate and protein should be distributed over three meals. This means you will usually take one capsule at breakfast, one at lunch and another at dinner. To gain optimal benefit, avoid the intake of food containing fat between meals, such as biscuits, chocolate and savory snacks.
2) Usual Pediatric Dose for Obesity:
12 years or older:120 mg orally three times a day with each main meal containing fat.
The dose may be taken during the meal or within 1 hour of completing the meal.