Contacting Information :
Contact person : Thyen
Skype :live:simeiquan-zhang
WhatsApp : +8618038176818
E-mail : zhangyinglong@ycphar.com
Website : www.sellsteroid.com
Quick Detail:
| CAS No.: | 191217-81-9 |
| Synonyms: | (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole Dihydrochloride Monohydrate; Pramipexole dihydrochloride; Pramipexole dihydroch; (S)-2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride PPX dihydrochloride; Pramipexole; Pramipexole 2HCl Monohydrate;Pramipexole Dihydrochloride Monohydrate; |
| Formula: | C10H21Cl2N3OS |
| Exact Mass: | 301.07800 |
| Molecular Weight: | 302.26400 |
| Appearance : | white to off-white crystalline powder |
| Boiling Point: | 378ºC at 760 mmHg |
| Flash Point: | 182.4ºC |
| Vapor Pressure: | 9.93E-11mmHg at 25°C |
| PSA: | 88.41000 |
| LogP: | 4.09400 |
Description:
Pramipexole (Mirapex, Mirapexin, Sifrol) is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS).Pramipexole has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.Only immediate-release pramipexole (Mirapex) is approved to treat either Parkinson symptoms or RLS. Extended-release pramipexole (Mirapex ER) is approved only to treat Parkinson symptoms.In a single controlled study of twenty one patients, pramipexole was found to be highly effective in the treatment of bipolar depression. Treatment was initiated at 0.125 mg three times a day and increased at a rate of 0.125 mg three times a day to a limit of 4.5 mg daily until the patients' condition satisfactorily responded to the medication or they could not abide the side effects. The final average dosage was 1.7 ± 0.9 mg daily. The incidence of hypomania in the treatment group was no greater than in the control group, although the size of the study is too small to determine risks for manic switch.
Applications:
Pramipexole dihydrochloride is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) andrestless legs syndrome (RLS). It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder.It is also being investigated for the treatment of clinical depression and fibromyalgia.pramipexole hydrochloride
COA :
| ITEMS | STANDARDS | RESULTS |
| Appearance | A white to off white powder | White powder |
| Identification | A. Meets the requirement | Complies |
| B. IR: similar to Reference Substance | Complies | |
| Loss on drying | ≤0.5% | 0.21% |
| Specific Rotation | +10.0°~+13.0° | +10.8° |
| Related Substances | Any single impurity ≤0.1% Total impurity ≤0.8% | 0.05% 0.10% |
| Purity By HPLC R-isomer | ≤0.15% | 0.10 |
| Residue on ignition | ≤0.1% | 0.05% |
| Residual solvents | Isopropyl alcohol ≤5000ppm Ethyl Acetate ≤5000ppm | 150ppm 250ppm |
| Heavy metals | ≤10ppm | Complies |
| Chlorides | ≤0.05% | Complies |
| Assay | 98%~102.0% | 99.8% |
| Conclusion | Analyse according to Factory Standard , Conform | |
Payments
As far as payment methods are considered, we accept a number of secure payment methods, customers can pay to us through any of the payment methods mentioned below:-
Western Union: Western Union Money Transfer, a very famous and secure money transfer method is accepted by us. Our customer who desire to pay us through this method can transfer payment to us by using WU. To pay us through WU, after placing your order, go to your nearest WU franchise, make the payment there and confirm us the MTCN. After receiving the payment we will process your order.
Money Gram: We also accept Money Gram, to pay us through Money Gram, after placing your order please contact us to get the payment sending details. After that, go to your nearest Money Gram franchise, make your payment and confirm us the Reference Number provided by the money gram at the above email address.
We accept payments via Western Union or Money Gram only. We don’t accept PayPal anymore, that we were doing in past but now we are not able to use PayPal anymore.(Some of the products we deals in are highly banned, so credit card and bank wire will not be the safe & secure for both of buyer and seller. For these type of orders, Western Union and Money Gram are most safe and secure payment methods).
Bit Coins: Bit Coins are also accepted by us, if you want to pay us through Bit Coins, please contact us, we will send you our Bit Coin address, you will send us payment at that address and we will ship your order.
