Pregabalin
Contact : Mr.Thyen
Email us at thyen.zhang@gmail.com
Whatsapp : +86 180 3817 6818
product name: Pregabalin
CAS:148553-50-8
Molecular Formula: C8H17NO2
Molecular Weight :159.23
Melting Point:194-196 degree centigrade
Boiling Point:274 degree centigrade at 760 mmHg
Flash Point:119.5 degree
centigrade
Density: 0.997 g/cm3
Assay :99%
Appearance: White or faint white crystal powder
Function: The drug is in the development of one of the most promising drug in epilepsy drug treatment, the better curative
effect and drug delivery is more convenient. It can also be used in the treatment of pain and anxiety.
Usage: A GABA Analogue Used as an Anticonvulsant
Delivery: Sent out Within 12 Hours After Payment Confirmed
Shipping: Express Courier(EMS, DHL, UPS, TNT, FedEx)
Packing: 25kg/ Paper Barrel or as Your Demand
Product Categories: APIs;Miscellaneous Biochemicals;Intermediates & Fine Chemicals;
Neurochemicas;Pharmaceuticals; compounds
2. Product Description:
Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic
used to treat peripheral neuropathic pain and fibromyalgia.Pregabalin is an anticonvulsant drug used for neuropathic pain, as an adjunct therapy for partial seizures, and in generalized anxiety disorder. It was designed as a more potent successor to gabapentin. Pregabalin is marketed by under the trade nam.
Pregabalin is used to relieve neuropathic pain (pain from damaged nerves) that can occur in your arms,
hands, fingers, legs, feet, or toes if you have diabetes or in the area of your rash if you have had shingles (a painful rash that occurs after infection with herpes zoster). It is also used to treat fibromyalgia
(a long-lasting condition that may cause pain, muscle stiffness and tenderness, tiredness, and difficulty falling
asleep or staying asleep). Pregabalin is used with other medications to treat certain types of seizures in
people with epilepsy. Pregabalin is in a class of medications called anticonvulsants. It works by decreasing the number of pain signals that are sent out by damaged nerves in the body.
3. Application:
Pregabalin is a white to off white, crystalline solid with a pKa1 of 4.2 and a pKa2
of 10.6. It is freely soluble in water and both basic and acidic aqueous solutions. The log of the partition coefficient (n-octanol/0.05M phosphate buffer) at pH 7.4 is 1.35.
LYRICA (pregabalin) Capsules are administered
orally and are supplied as imprinted hard-shell capsules containing 25, 50, 75, 100, 150, 200, 225, and 300 mg of pregabalin, along with lactose
monohydrate, cornstarch, and talc as inactive ingredients. The capsule shells contain gelatin and
titanium dioxide. In addition, the orange capsule shells contain red iron oxide and the white capsule
shells contain sodium lauryl sulfate and colloidal silicon dioxide. Colloidal silicon dioxide is a
manufacturing aid that may or may not be present in the capsule shells. The imprinting ink contains
shellac, black iron oxide, propylene glycol, and potassium hydroxide.
LYRICA (pregabalin) oral solution, 20 mg/mL, is administered orally and is supplied
as a clear, colorless
solution contained in a 16 fluid ounce white HDPE bottle with a Polyethylene lined closure. The oral solution contains 20 mg/mL of pregabalin, along with methylparaben,
propylparaben, monobasic sodium phosphate anhydrous, dibasic sodium phosphate anhydrous, sucralose, artificial strawberry #11545 and purified water as inactive ingredients.
4. Pregabalin COA:
ITEMS | STANDARDS | RESULTS |
Appearance | A white to off white powder | White powder |
Identification | A. Meets the requirement | Complies |
B. IR: similar to Reference Substance | Complies | |
Loss on drying | ≤0.5% | 0.21% |
Specific Rotation | +10.0°~+13.0° | +10.8° |
Related Substances | Any single impurity ≤0.1% | 0.05% |
Purity By HPLC R-isomer | ≤0.15% | 0.10 |
Residue on ignition | ≤0.1% | 0.05% |
Residual solvents | Isopropyl alcohol ≤5000ppm | 150ppm |
Heavy metals | ≤10ppm | Complies |
Chlorides | ≤0.05% | Complies |
Assay | 98%~102.0% | 99.8% |
Conclusion | Analyse according to Factory Standard , Conform |
5. Our advantages:
Fast Delivery | Delivery within 24 hours upon receipt of your payment |
Quality | Quality can be promised. Hot sell to Worldwide |
Payment Terms | Bank Transfer, Western Union, Bitcoin and MoneyGram Available |
Sample | Sample available at any time |
Tracking number | Tracking your order at any time Inform your order's further new situation at any time |
Package | Professional packing with professional materials |