Promethazine Hydrochloride CAS 58-33-3

Promethazine Hydrochloride CAS 58-33-3

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details


Promethazine Hydrochloride

 

Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818

 

Description:

Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. The drug has strong sedative and weak antipsychotic effects.It also reduces motion sickness and has antiemetic and anticholinergic properties(via its action on the dopamine receptor D2). In some countries it is prescribed for insomnia when benzodiazepines are contraindicated. It is available in many countries under many brand names. Promethazine was developed in the mid 1940s when a team of scientists from Rhône-Poulenc laboratories were able to synthesize it from phenothiazine and a diamine side chain of diphenhydramine

Promethazine hydrochloride occurs as a white to faint yellow, practically odorless,crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. It is soluble in water and freely soluble in alcohol.


Product Name

Promethazine hydrochloride

Synonym

phenothiazine hydrochloride;Promethazine Hcl

CAS

58-33-3

MF

C17H21ClN2S

MW

320.88

EINECS

200-375-2

Purity

99%

Appearance

White Solid

Melting Point

230-232°C

Grade

Pharma Grade

Usage

For the treatment of allergic disorders,and nausea/vomiting.

Packing

Discreet package

Storage

Store in cool and dry area and keep away from direct sunlight.



Specification:

ItemSpecification

Result

DescriptionWhite crystalline powder

White crystalline powder

IdentificationIR,UV conform

Conform

Loss on drying≤0.5ml

0.21ml

Residue on ignitionNot more than 0.2%

0.06ml

IronNot more than 0.005%

0.0018%

Heavy metalsNot more than 0.001%

0.0006%

Related substancesTotal: Not more than 1.0%
Individual: Not more than 0.5%

0.32%
0.14%

E-isomerNot more than 0.3%

0.19%

Organic volatile impurities

ConformsConforms
Assay99.0~101.0%

99.51%

Conclusion

Conform with USP30


Application:


Promethazine is used to prevent and treat nausea and vomiting related to certain conditions(such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It may be used to help you feel sleepy/relaxed before and after surgery or to help certain narcotic pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the common cold.

Promethazine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as acetylcholine) and by acting directly on certain parts of the brain.


Use:


1)Antihistaminic, antiemetic,CNS depressant.


2)stool softener.


3)With aminophylline in the treatment of asthma.


4)For the treatment of allergic disorders, and nausea/vomiting.


5)Dubbed hibernation and injection for artificial hibernation.


Advantage:


1,High quality with competitive price
1)Standard: Enterprise Standard
2)All Purity≥99%
3)We are manufacturer and can provide factory price.


2,Fast and safe delivery
1)Parcel can be sent out in 24 hours after payment. Tracking number available
2)Secure and discreet shipment.Various transportation method for your choice.
3)Customs pass rate ≥99%


3,We have clients throughout the world.
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.



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