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Raloxifene hydrochlorideis an estrogen agonist/antagonist, commonly referred to as a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. Raloxifene hydrochloride (HCl) has the empirical formula C28H27NO4SHCl, which corresponds to a molecular weight of 510.05. Raloxifene HCl is an off-white to pale yellow solid that is very slightly soluble in water.
Product name: Raloxifene hydrochloride
CAS : 82640-04-8
Molecular Formula: C28H28ClNO4S
Molecular Weight: 473.58328
Melting point: 143-147degree centigrade
Boiling Point: 728.2 degree centigrade at 760 mmHg
Flash Point: 394.2 degree centigrade
Water solubility:DMSO: 28 mg/mL, soluble
Appearance: Light yellow solid
Indications: This product is mainly used to prevent postmenopausal osteoporosis
Usage of Raloxifene Hydrochloride : Used for the prevention and treatment of postmenopausal osteoporosis, can significantly reduce the incidence of vertebral fractures.
Reduction in the incidence of invasive breast cancer in postmenopausal women with osteoporosis.
Reduction in the incidence of invasive breast cancer in postmenopausal women at high risk for developing the disease. Effect comparable to that of tamoxifen in reducing the risk of invasive breast cancer (STAR trial). No effect on the risk of lobular carcinoma in situ or ductal carcinoma in situ (STAR trial). Effect on breast cancer incidence in women with BRCA1 or BRCA2 genetic mutations not established.
Function of Cyproterone:
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This product and ethinylestradiol compound, can be used as a short-acting oral contraceptives.Also has the obvious curative effect for female acne.
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With resistance to salt cortex hormone and antiandrogen role, has a broad market prospect.