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Repaglinide is an antidiabetic drug in the class of medications known as meglitinides. Repaglinide is an oral medication used in addition to diet and exercise for blood sugar control in type 2 diabetes mellitus. The mechanism of action of repaglinide involves promoting insulis release from β-islet cells of the pancreas; like other antidiabetic drugs, a main side effect concern is hypoglycemia.
| Product Name | Repaglinide |
| Alias | Repaglinide; (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl] aminocar bonylmethyl]benzoic acid, Novonorm; Prandin; RepaglinideG0D(ai); |
| CAS No | 135062-02-1 |
| Einecs No | 1312995-182-4 |
| Molecular Formula | C27H36N2O4 |
| Molecular Weight | 452.59 |
| Purity | 99% |
| Melting Point | 129-130.2 °C |
| Appearance | White crytalline powder |
| Grade | Pharma Grade |
| Usage | Non-sulfonylurea oral hypoglycemic agent. Used as an antidiabetic |
| Usage | The R-enantiomer showed only weak hypoglycemic activity. |
| Usage | A KIR6 (KATP) channel blocker; Antineoplastic |
Usage And Dosage
Repaglinide should be taken before the main meal (ie, before meals). In the 30 minutes of oral administration of insuli secretion response. Usually within 15 minutes before the meal taking the drug, medication time can also be mastered in the morning 0 to 30 minutes.
Please follow the medications. Dosage varies from person to person, depending on individual blood sugar, recommended starting dose of 0.5 mg, after the need for weekly or every two weeks to adjust.
Patients receiving other oral hypoglycemic agents can be treated directly with repaglinide. The recommended starting dose is 1 mg. The maximum recommended single dose of 4mg, when taking meals. But the maximum daily dose should not exceed 16mg.
Uses
1. Anti-diabetic medicine. Oral non-sulfonylurea hypoglycemic agent, for the treatment of type 2 diabetes.
2. Used as hypolycemic agent.
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