Topiramate CAS 97240-79-4

Topiramate CAS 97240-79-4

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details

Topiramate CAS 97240-79-4

Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


Topiramate-----------Quick Details
 
Topiramate Product Name: Topiramate
Topiramate CAS: 97240-79-4
Topiramate MF: C12H21NO8S
Topiramate MW: 339.36
Topiramate EINECS: 200-659-6
Topiramate Product Categories: Active Pharmaceutical Ingredients;APIs;Health & Beauty;Carbohydrates & Derivatives;Pharmaceuticals;Glutamate receptor;Intermediates & Fine Chemicals;API;TOPAMAX;Pharmaceutical raw materials
Topiramate Melting point : 125°C
Topiramate Storage temp. : 2-8°C
Topiramate Chemical Properties : White-to-Off-White Crystalline Powder
Topiramate Usage : anticonvulsant, antimigraine, GABA-A agonist, AMP/kinate glutamate receptor antagonist, carbonic anhydrase inhibitor
 
 
Topiramate-----------Description
 
Topiramate is an anticonvulsant (antiepilepsy) drug. In late 2012, topiramate was approved by the United States Food and Drug Administration (FDA) in combination with phentermine for weight loss. The drug had previously been used off-label for this purpose.
 
Topiramate was originally produced by Ortho-McNeil Neurologics and Noramco, Inc., both divisions of the Johnson & Johnson Corporation. This medication was discovered in 1979 by Bruce E. Maryanoff and Joseph F. Gardocki during their research work at McNeil Pharmaceutical.
 
Topiramate COA
 

Items 
Specifications
 
Results
AppearanceWhite to off-white powder, Freely soluble in dichloromethaneWhite powder, Freely soluble in dichloromethane
IdentificationInfared AbsorptionComplies
The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation, as obtained in the assaycomplies
Specific rotationBetween -28.6°and -35.0°, measured at 20°-32.8°
Waternot more than 0.5%0.12%
residue on ignitionnot more than 0.2%0.11%
Heavy metalsnot more than 0.001%complies
related compounds by HPLC(Test1)Fructose not more than 0.3% Compound A not more than 0.3% Other individual impurity not more than 0.1% Total impurities not more than 0.5%Fructose: 0.03%
Compound A:0.04%individual impurity Total impurities: 0.07%
Particle size90% less than 350 micronscomplies
Limit of sulfamate and sulfateSulfamate ion not more than 0.10% Sulfate ion not more than 0.10%complies
Residual SolventMethylene Chloride not more than 250μg/gnot detected
Acetone not mor than 2500μg/g
Isopropanol not more than 5000μg/g
Ethanenitrile not more than 400μg/g
n-hexane not more than 290μg/g
Ethyl Acetate not more than 2500μg/g
Pyridine not more than 100μg/g
AssayTopiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis99.80%
ConclustionThe material complies with respect to USP35
 

 
Topiramate Medical uses
 
Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant. In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and developmental delay.
 
Topiramate is also Food and Drug Administration (FDA) approved for, and most frequently prescribed for, the prevention of migraines. The drug is also used to treat migraines due to the effect it has on the blood vessels in the brain. It has been found to be increasingly effective for migraine sufferers with limited side effects .


Our advantages:

1, High quality with competitive price: 
1)Standard: Enterprise Standard
2)All Purity≥99%
3)We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
1)Parcel can be sent out in 24 hours after payment. Tracking number available. 
2)Secure and discreet shipment. Various transportation methods for your choice. 
3)Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring. 
 
3, We have clients throughout the world.
1)Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire. 
2)Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers. 

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us. 
 
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,  caused by us, we will send you free goods for replacement or refund your loss.
 
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.

Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price. 

Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
We'd like to accept bank transfer, Western Union or Paypal or Moneygram
 
Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
 For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q7. Do  you  have  any  reshipment  policy ?  
we have good after-sale service and re-shipment policy if the parcel  lose
Our long association with  our clients has brought great benefits
We always take the upmost care in the packaging of our products 
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible  will seize a small number of packages.
In this circumstance we promise reship free  to establish  long term relationship
 
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost should undertake by your side.


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