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7-Keto-dehydroepiandrosterone is a chemical that is formed in the body.is a "parent hormone" produced by glands near the kidneys. But unlike DHEA, 7-Keto-dehydroepiandrosterone is not converted to steroid hormones such as androgen and estrogen. Taking 7-Keto-dehydroepiandrosterone by mouth or applying it to the skin does not increase the level of steroid hormones in the blood.People take 7-Keto-dehydroepiandrosterone to speed up the metabolism and heat production to promote weight loss. 7-Keto-dehydroepiandrosterone is also used to improve lean body mass and build muscle, increase the activity of the thyroid gland, boost the immune system, enhance memory, and slow aging.
7-Keto-dehydroepiandrosterone is mostly known to not be hormonal; 7-Keto-dehydroepiandrosterone can interact with steroid metabolism but the exact manner in which 7-Keto-dehydroepiandrosterone does it not fully elucidated. 7-Keto-dehydroepiandrosterone does appear to have anti-cortisol mechanisms as the enzymes that activate cortisol (from the relatively inactive precursors of cortisone and corticosterone) are the same that interconvert these oxygenated metabolites. Although 7-Keto-dehydroepiandrosterone appears to be anti-cortisol by its mechanisms, there is insufficient evidence to support these mechanisms in the body following oral supplementation.
Studies using 7-Keto-dehydroepiandrosterone tend to note an increased metabolic rate later on during a caloric restriction period (which is secondary to reducing the rate of metabolic rate decline associated with dieting, and becoming a relative increase) although the quantity of data on this is pretty minimal if we exclude studies with possible conflicts of interest or those that use 7-Keto-dehydroepiandrosterone alongside a multitude of supplements.7-Keto-dehydroepiandrosterone appears to be a somewhat promising non-hormonal fat burning agent but requires more evidence on both of those claim.
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