Ethinylestradiol Raw Powder

Ethinylestradiol Raw Powder

Contact : Mr.Thyen------------------------------- Email us at zhangyinglong@ycphar.com Whatsapp : +86 180 3817 6818

Product Details


Ethinylestradiol


Contact : Mr.Thyen

Email us at zhangyinglong@ycphar.com

Whatsapp : +86 180 3817 6818


CAS NO: 57-63-6
Molecular Weight: 296.41
Molecular Formula: C20H24O2
EINECS: 200-342-2
Appearance: White powder
Melting Point: 180~186
Loss on drying: ≤ 1.0%
Purity: 98%
Storage: Keep it under seal in cool and dark place
use: Use estrogen drugs
pack: as requirments

Description:
1)Ethinylestradiol is a man-made form of the naturally occurring female hormone called oestrogen. It is prescribed to treat period (menstrual) problems, and also to help ease menopausal symptoms. It is usually prescribed alongside another female hormone called a progestogen.


Ethinyl estradiol also sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl? Stradiol, is a derivative of 17β -estradiol (E2), the major endogenous estrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly used medications for this purpose.


Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism.


EE is released into the environment as a xenoestrogen from the urine and feces of people who take it as a medication.


2)Estrogen drugs. Ethylene female role with phenol, but 20 times more effective. With use of hormonal contraception pregnancy merge, inhibit ovulation synergy, can strengthen the contraceptive effect, and can reduce breakthrough bleeding and other side effects. In addition, can also be used for menstrual disorders, such as amenorrhea, months after less and menopause syndrome and uterine development not congruent. For contraceptive medicinal preparation.


Application:

As a sex hormone, E2 has several different functions in women's fertility. First, it helps to build and protect the lining of the fallopian tubes, vagina, and uterus. This role is critical to get the embryo to attach to the uterine wall. Many women who experience fertility problems have low levels of estradiol. Second, E2 maintains the oocytes, or egg cells, in the ovary. Healthy oocytes lead to healthy embryos. Only the best oocyte is selected at each ovulation period to be released and possibly.


As a tissue builder, E2 seems to help protect women from heart disease by raising the levels of HDL, the "good" cholesterol in the body. When hormone levels drop in postmenopausal women, their risk of heart disease increases. E2 also helps protect bone density in both men and women by participating in a messaging system that suppresses an overly rapid growth of immune cells in the bone. If more immune cells are allowed to grow, they can block calcium absorption in the bone. This is why men with lower levels of this hormone in their system have been found to be more susceptible to hip fractures.

COA

Item

Specification

Results

Appearance

White to creamy white, odorless, crystalline powder.

white crystalline powder

Solubility

Insoluble in water; soluble in alcohol, in chloroform, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides.

Conforms

Identification

A:IR B:UV

Conforms

Specific optical rotation

-28°~ -29.5°

-28.3°

Melting range

180~186ºC

182.5~185.3ºC

Loss on drying

≤1.0%

0.45%

Residual Solvents

Acetone≤0.5%

0.08%

Assay

97.0~102.0% (on the dried basis)

99.43%

Particle Size

90% ≤10μ

Conforms

Conclusion

The product complies with specification in USP34



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