Ethinylestradiol
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CAS NO: 57-63-6
Molecular Weight: 296.41
Molecular Formula: C20H24O2
EINECS: 200-342-2
Appearance: White powder
Melting Point: 180~186
Loss on drying: ≤ 1.0%
Purity:
98%
Storage: Keep it under seal in cool and dark place
use: Use estrogen drugs
pack: as requirments
Description:
1)Ethinylestradiol is a man-made form of the naturally occurring female hormone called oestrogen. It is prescribed to treat period (menstrual)
problems, and also to help ease menopausal symptoms. It is usually prescribed alongside another female hormone called a progestogen.
Ethinyl estradiol also sometimes written as ethinylestradiol, ethynyl estradiol, or ethinyl?
Stradiol, is a derivative of 17β -estradiol (E2), the major endogenous estrogen in humans. EE is an orally bioactive estrogen used in many formulations of combined oral contraceptive pills. It is one of the most commonly
used medications for this purpose.
Estinyl was a preparation of EE alone that was used for the management of menopausal symptoms and female hypogonadism.
EE is released into the environment as a xenoestrogen from the
urine and feces of people who take it as a medication.
2)Estrogen drugs. Ethylene female role with phenol, but 20 times more effective. With use of hormonal contraception pregnancy merge, inhibit ovulation synergy,
can strengthen the contraceptive effect, and can reduce breakthrough bleeding and other side effects. In addition, can also be used for menstrual disorders, such as amenorrhea, months after less and menopause syndrome and
uterine development not congruent. For contraceptive medicinal preparation.
Application:
As a sex hormone, E2 has several different functions in women's fertility. First, it helps to build and protect the lining of the fallopian tubes, vagina, and uterus.
This role is critical to get the embryo to attach to the uterine wall. Many women who experience fertility problems have low levels of estradiol. Second, E2 maintains the oocytes, or egg cells, in the ovary. Healthy oocytes
lead to healthy embryos. Only the best oocyte is selected at each ovulation period to be released and possibly.
As a tissue builder, E2 seems to help protect women from heart disease by raising the levels of HDL, the
"good" cholesterol in the body. When hormone levels drop in postmenopausal women, their risk of heart disease increases. E2 also helps protect bone density in both men and women by participating in a messaging system
that suppresses an overly rapid growth of immune cells in the bone. If more immune cells are allowed to grow, they can block calcium absorption in the bone. This is why men with lower levels of this hormone in their system
have been found to be more susceptible to hip fractures.
COA
Item | Specification | Results |
Appearance | White to creamy white, odorless, crystalline powder. | white crystalline powder |
Solubility | Insoluble in water; soluble in alcohol, in chloroform, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides. | Conforms |
Identification | A:IR B:UV | Conforms |
Specific optical rotation | -28°~ -29.5° | -28.3° |
Melting range | 180~186ºC | 182.5~185.3ºC |
Loss on drying | ≤1.0% | 0.45% |
Residual Solvents | Acetone≤0.5% | 0.08% |
Assay | 97.0~102.0% (on the dried basis) | 99.43% |
Particle Size | 90% ≤10μ | Conforms |
Conclusion | The product complies with specification in USP34 |
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2. High Quality:
1)Standard: Enterprise Standard
2)Purity:
99%
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