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Carnosine (beta-alanyl-L-histidine), featuring the characteristic imidazole-ring, is a dipeptide molecule, made up of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.
It has been proven to scavenge reactive oxygen species (ROS) as well as alpha-beta unsaturated aldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. It also buffers pH in muscle cells, and acts as a neurotransmitter in the brain.
Carnosine can increase the Hayflick limit in human fibroblasts, as well as appearing to reduce the telomere shortening rate.
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